MOTS-C

CAS Number: 1610359-13-0
Molecular Formula: C₁₃₆H₂₁₇N₄₃O₂₇
Molecular Weight: 2177.6 g/mol
B: MRWQEMGYIFYPRKLR

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded by the mitochondrial genome. It plays a unique regulatory role in cellular metabolism by translocating to the nucleus in response to metabolic stress, where it modulates the expression of genes related to mitochondrial function and energy homeostasis. Its activity has drawn interest for its potential in longevity, metabolic disease, and exercise adaptation studies.
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Research Applications

MOTS-c is currently being explored in a variety of experimental settings, particularly for its impact on:

Metabolic Regulation: Investigating glucose utilization, fatty acid oxidation, and insulin sensitivity.

Stress Response: Exploring its role in cellular protection during metabolic or oxidative stress.

Exercise Physiology: Evaluating improvements in endurance, mitochondrial biogenesis, and energy output.

Aging and Longevity: Studying age-related mitochondrial decline and potential anti-senescence pathways.

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For Research Use Only

MOTS-c provided by PeptideStock.com is intended strictly for laboratory and research purposes. It is not for human use, clinical treatment, or consumption. Proper handling and storage procedures should be followed by qualified professionals.